Formulation of Gel HandSanitizer Ethanol Extract Salam Leaves with Carbopol and Na CMC as Gelling Agent
Abstract
Hand sanitizer gel has been widely used as a way to maintain hand health and hygiene that is practical and easy to carry. Generally hand sanitizer gels contain alcohol compounds as antiseptics to kill bacteria, but the use of antiseptic gels that contain alcohol in the long term can cause irritation. Therefore, we need natural alternative materials that are friendly to the skin and do not irritate the skin, one of the plants that has antibacterial power is bay leaf (Syzygium polyanthum). The purpose of this study was to determine the formulation and physical properties of hand sanitizer gel from bay leaf extract (Syzygium polyanthum). This research is an experimental study with research data presented descriptively. The gel was made in three formulas with different carbopol concentrations, namely 0.2%, 0.5%, and 3% Na CMC. The evaluation of the physical properties of the gel included organoleptic, homogeneity, dispersibility, adhesion, and pH tests. The results of the evaluation showed that formula 1 (Na CMC 3%, ethanolic extract of bay leaf 12.5%) and formula 2 (carbopol 0.2%, ethanolic extract of bay leaf 12.5%) fulfilled all the requirements for evaluating the physical properties of the gel which included organoleptic test, homogeneity, spreadability, adhesion, and pH. While formula 3 (carbopol 0.8%, ethanol extract of bay leaf 25%) did not meet the physical properties test, namely the dispersion test.
References
2. Swaminathan B, Barrett TJ, Hunter SB, Tauxe R V, Force CDCPT. PulseNet: the molecular subtyping network for foodborne bacterial disease surveillance, United States. Emerg Infect Dis. 2001;7(3):382.
3. Subramaniam P, Nandan N. Effect of xylitol, sodium fluoride and triclosan containing mouth rinse on Streptococcus mutans. Contemp Clin Dent. 2011;2(4):287.
4. Ismail A, Ahmad WANW. Syzygium polyanthum (Wight) Walp: a potential phytomedicine. Pharmacogn J. 2019;11(2).
5. Astari TY, Hasan R, Isnanta R. Serum IL-10 levels in acute coronary syndrome Wistar mice model with Salam leaf extract (Syzygium polyanthum) administration.
6. Indra Dewi Z. The Effect Of Leave Extract (Paederia Foetida) On The Instruction Zone Of The Bacteria Escherichia Coli (Used As A Biology Learning Source). University of Muhammadiyah Malang; 2019.
7. Sayuti NA. Formulation and physical stability test of Chinese ketepeng leaf extract gel preparation (Cassia alata l.). J Kefarmasian Indones. 2015;74–82.
8. jin An H, Lee Y, Liu L, Lee S, duk Lee J, Yi Y. Physical and chemical stability of formulations loaded with taxifolin tetra-octanoate. Chem Pharm Bull. 2019;67(9):985–91.
Journal of Public Health and Pharmacy has CC-BY-SA or an equivalent license as the optimal license for the publication, distribution, use, and reuse of scholarly work. Authors who publish with this journal retain copyright and grant the journal the right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
