Antibiotic Resistance in Cases of Bacterial Meningitis: Literature Review
Keywords:
Bacterial Meningitis, Antibiotic Resistance, Streptococcus Pneumoniae
Abstract
Introduction: Meningitis is an infectious disease that attacks the cerebral membrane or swallows. Meningite is among the ten most dangerous diseases in the world. The disease can affect both children and adults. The cause of this disease can be bacteria, viruses, fungi, or aseptic. Most cases of viral meningitis usually heal themselves and are not fatal, but in severe cases, such as bacterial, biased, life-threatening.
Methods: Articles related to bacterial meningitis taken from databases like Google Scholar, Pubmed and Portal Garuda over the last 5 years (2020- 2024). Use keywords: "Bacterial meningitis", "symptoms", "therapy", "antibiotic resistance
Results: Based on studies that have been carried out, antibiotic resistance rates in cases of bacterial meningitis are very high and vary. Streptococcus pneumonia as one of the most common causes has high levels of resistance to antibiotics of the penicillin group.
Conclusion: With the growing number of rapid, reliable and accurate diagnostics and follow-up examinations, it can cope with the incidence of antibiotic resistance in bacterial meningitis.
References
1. Gusti, I., Kurnia, N., Wiartika, A., Putu, L., & Kamelia, L. (2022). Laporan Kasus: Meningitis Bakterial. In Ganesha Medicina Journal (Vol. 2, Issue 2). Tersedia dari: https://ejournal.undiksha.ac.id/index.php/GM/article/view/47386/23126
2. Fitriati, D., & Gibran, I. (2021). Sistem Pakar Diagnosis Penyakit Meningitis Menggunakan Metode Forward Chaining (Vol. 12, Issue 1). https://jurnal.umj.ac.id/index.php/just-it/index
3. Widyastuti, P., Nurul Utami, H., & Fardi Anugrah, M. (2023). LMJ 2(2) (2023) Lombok Medical Journal Meningitis Bakterial: Epidemiologi, Patofisiologi, dan Penatalaksanaan. https://doi.org/10.29303/lmj.v2i2.2962
4. Sunwoo, J. S., Shin, H. R., Lee, H. S., Moon, J., Lee, S. T., Jung, K. H., Park, K. il, Jung, K. Y., Kim, M., Lee, S. K., & Chu, K. (2021). A hospital-based study on etiology and prognosis of bacterial meningitis in adults. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-85382-4
5. Wall EC, Chan JM, Gil E, Heyderman RS. Acute bacterial meningitis. Current Opinion in Neurology [Internet]. 2021 Mar 26;34(3):386–95. Available from: https://doi.org/10.1097/wco.0000000000000934
6. Aulia, R., & Sukma Rita, R. (2023). Tinjauan Pustaka Potensi Ekstrak Daun Ruku-Ruku (Ocimum tenuiflorum) Terenkapsulasi Nanopartikel Kitosan Sebagai Agen Terapi Meningitis Berbasis Bahan Alam. 46(2), 474–482. http://jurnalmka.fk.unand.ac.id
7. van de Beek, D., Brouwer, M. C., Koedel, U., & Wall, E. C. (2021). Community-acquired bacterial meningitis. In The Lancet (Vol. 398, Issue 10306, pp. 1171–1183). Elsevier B.V. https://doi.org/10.1016/S0140-6736(21)00883-7
8. Runde TJ, Anjum F, Hafner JW. Bacterial Meningitis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470351/
9. Sherzodjon Taxirovich, A. (2023). International Journal of Scientific Trends-(IJST) The Main Etiological Factors, Methods of Prevention and Treatment of Meningitis. 2(2).
10. Peng, X., Zhu, Q., Liu, J., Zeng, M., Qiu, Y., Zhu, C., Cheng, Y., Zhou, Y., Xu, Y., Chen, M., Wen, Z., Chen, Y., Li, R., Tong, J., Shan, Q., Lin, D., Wu, S., Zhuo, Z., Wang, C., … Wan, C. (2021). Prevalence and antimicrobial resistance patterns of bacteria isolated from cerebrospinal fluid among children with bacterial meningitis in China from 2016 to 2018: a multicenter retrospective study. Antimicrobial Resistance and Infection Control, 10(1). https://doi.org/10.1186/s13756-021-00895-x
11. Rostamian M, Lorestani RC, Jafari S, Mansouri R, Rezaeian S, Ghadiri K, et al. A systematic review and meta-analysis on the antibiotic resistance of Neisseria meningitidis in the last 20 years in the world. Indian Journal of Medical Microbiology [Internet]. 2022 Jul 1;40(3):323–9. Available from: https://doi.org/10.1016/j.ijmmb.2022.05.005
12. Okparasta, A., & Susan, D. (n.d.). Characteristics, Patterns of Pathogens, and Antibiotics Resistance of Bacterial Meningitis at RSUP dr. Mohammad Hoesin Palembang. 2020. Jurnal Kedokteran dan Kesehatan: Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya; 7(3). https://doi.org/10.32539/JKK.V7I3.11442
13. Namale, V. S., Kim, C., Sun, Y., Curcio, A., Navis, A., Idro, R., & Thakur, K. T. (n.d.). Etiologies of community acquired bacterial meningitis and antibiotic resistance patterns in Africa over the last 30 years: A Systematic Review Corresponding Author*. In Journal of Neurology & Neurophysiology (Vol. 2020).
14. Cabellos, C., Guillem, L., Pelegrin, I., Tubau, F., Ardanuy, C., Gudiol, F., Ariza, J., & Viladrich, P. F. (2022). Penicillin- and Cephalosporin-Resistant Pneumococcal Meningitis: Treatment in the Real World and in Guidelines. Antimicrobial Agents and Chemotherapy, 66(12). https://doi.org/10.1128/aac.00820-22
15. Ali, S. A., Taj, M. K., & Ali, S. H. (2021). Antimicrobial resistance pattern of bacterial meningitis among patients in quetta, pakistan. Infection and Drug Resistance, 14, 5107–5120. https://doi.org/10.2147/IDR.S339231
16. Zheng, G., Shi, Y., Cao, Y., Qian, L., Lv, H., Zhang, L., & Zhang, G. (2022). Clinical Feature, Therapy, Antimicrobial Resistance Gene Distribution, and Outcome of Nosocomial Meningitis Induced by Multidrug-Resistant Enterobacteriaceae—A Longitudinal Cohort Study From Two Neurosurgical Centers in Northern China. Frontiers in Cellular and Infection Microbiology, 12. https://doi.org/10.3389/fcimb.2022.839257
17. Ishikawa K, Matsuo T, Suzuki T, Kawai F, Uehara Y, Mori N. Penicillin- and third-generation cephalosporin-resistant strains of Streptococcus pneumoniae meningitis: Case report and literature review. Journal of Infection and Chemotherapy [Internet]. 2022 May 1;28(5):663–8. Available from: https://doi.org/10.1016/j.jiac.2022.01.021
18. Willerton, L., Lucidarme, J., Walker, A., Lekshmi, A., Clark, S. A., Walsh, L., Bai, X., Lee-Jones, L., & Borrow, R. (2021). Antibiotic resistance among invasive Neisseria meningitidis isolates in England, Wales and Northern Ireland (2010/11 to 2018/19). PLoS ONE, 16(11 November). https://doi.org/10.1371/journal.pone.0260677
19. Henny Kristianti, G., Gusti Ngurah Made Suwarba, I., Sutriani Mahalini, D., Wayan Gustawan, I., & Made Gede Dwi Lingga Utama, I. (2020). Bacteria and Antibiotic Susceptibility Patterns of Cerebrospinal Fluid Isolated in Children with Bacterial Meningitis at Sanglah Hospital, Bali from 2016 to 2018. Clinical Neurology and Neuroscience, 4(3), 51. https://doi.org/10.11648/j.cnn.20200403.12
20. Kumar Bathija, S., Bano, S., & Tunio, S. A. (2024). Bacteriological Analysis And Antibiotic Resistance Trends In Bacteria Isolated From Cerebrospinal Fluid Of Suspected Bacterial Meningitis Patients At Hyderabad, Sindh. J. Biotechnol, 21(2), 387–391. https://doi.org/10.34016/pjbt.2024.21.02.922
2. Fitriati, D., & Gibran, I. (2021). Sistem Pakar Diagnosis Penyakit Meningitis Menggunakan Metode Forward Chaining (Vol. 12, Issue 1). https://jurnal.umj.ac.id/index.php/just-it/index
3. Widyastuti, P., Nurul Utami, H., & Fardi Anugrah, M. (2023). LMJ 2(2) (2023) Lombok Medical Journal Meningitis Bakterial: Epidemiologi, Patofisiologi, dan Penatalaksanaan. https://doi.org/10.29303/lmj.v2i2.2962
4. Sunwoo, J. S., Shin, H. R., Lee, H. S., Moon, J., Lee, S. T., Jung, K. H., Park, K. il, Jung, K. Y., Kim, M., Lee, S. K., & Chu, K. (2021). A hospital-based study on etiology and prognosis of bacterial meningitis in adults. Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-85382-4
5. Wall EC, Chan JM, Gil E, Heyderman RS. Acute bacterial meningitis. Current Opinion in Neurology [Internet]. 2021 Mar 26;34(3):386–95. Available from: https://doi.org/10.1097/wco.0000000000000934
6. Aulia, R., & Sukma Rita, R. (2023). Tinjauan Pustaka Potensi Ekstrak Daun Ruku-Ruku (Ocimum tenuiflorum) Terenkapsulasi Nanopartikel Kitosan Sebagai Agen Terapi Meningitis Berbasis Bahan Alam. 46(2), 474–482. http://jurnalmka.fk.unand.ac.id
7. van de Beek, D., Brouwer, M. C., Koedel, U., & Wall, E. C. (2021). Community-acquired bacterial meningitis. In The Lancet (Vol. 398, Issue 10306, pp. 1171–1183). Elsevier B.V. https://doi.org/10.1016/S0140-6736(21)00883-7
8. Runde TJ, Anjum F, Hafner JW. Bacterial Meningitis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470351/
9. Sherzodjon Taxirovich, A. (2023). International Journal of Scientific Trends-(IJST) The Main Etiological Factors, Methods of Prevention and Treatment of Meningitis. 2(2).
10. Peng, X., Zhu, Q., Liu, J., Zeng, M., Qiu, Y., Zhu, C., Cheng, Y., Zhou, Y., Xu, Y., Chen, M., Wen, Z., Chen, Y., Li, R., Tong, J., Shan, Q., Lin, D., Wu, S., Zhuo, Z., Wang, C., … Wan, C. (2021). Prevalence and antimicrobial resistance patterns of bacteria isolated from cerebrospinal fluid among children with bacterial meningitis in China from 2016 to 2018: a multicenter retrospective study. Antimicrobial Resistance and Infection Control, 10(1). https://doi.org/10.1186/s13756-021-00895-x
11. Rostamian M, Lorestani RC, Jafari S, Mansouri R, Rezaeian S, Ghadiri K, et al. A systematic review and meta-analysis on the antibiotic resistance of Neisseria meningitidis in the last 20 years in the world. Indian Journal of Medical Microbiology [Internet]. 2022 Jul 1;40(3):323–9. Available from: https://doi.org/10.1016/j.ijmmb.2022.05.005
12. Okparasta, A., & Susan, D. (n.d.). Characteristics, Patterns of Pathogens, and Antibiotics Resistance of Bacterial Meningitis at RSUP dr. Mohammad Hoesin Palembang. 2020. Jurnal Kedokteran dan Kesehatan: Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya; 7(3). https://doi.org/10.32539/JKK.V7I3.11442
13. Namale, V. S., Kim, C., Sun, Y., Curcio, A., Navis, A., Idro, R., & Thakur, K. T. (n.d.). Etiologies of community acquired bacterial meningitis and antibiotic resistance patterns in Africa over the last 30 years: A Systematic Review Corresponding Author*. In Journal of Neurology & Neurophysiology (Vol. 2020).
14. Cabellos, C., Guillem, L., Pelegrin, I., Tubau, F., Ardanuy, C., Gudiol, F., Ariza, J., & Viladrich, P. F. (2022). Penicillin- and Cephalosporin-Resistant Pneumococcal Meningitis: Treatment in the Real World and in Guidelines. Antimicrobial Agents and Chemotherapy, 66(12). https://doi.org/10.1128/aac.00820-22
15. Ali, S. A., Taj, M. K., & Ali, S. H. (2021). Antimicrobial resistance pattern of bacterial meningitis among patients in quetta, pakistan. Infection and Drug Resistance, 14, 5107–5120. https://doi.org/10.2147/IDR.S339231
16. Zheng, G., Shi, Y., Cao, Y., Qian, L., Lv, H., Zhang, L., & Zhang, G. (2022). Clinical Feature, Therapy, Antimicrobial Resistance Gene Distribution, and Outcome of Nosocomial Meningitis Induced by Multidrug-Resistant Enterobacteriaceae—A Longitudinal Cohort Study From Two Neurosurgical Centers in Northern China. Frontiers in Cellular and Infection Microbiology, 12. https://doi.org/10.3389/fcimb.2022.839257
17. Ishikawa K, Matsuo T, Suzuki T, Kawai F, Uehara Y, Mori N. Penicillin- and third-generation cephalosporin-resistant strains of Streptococcus pneumoniae meningitis: Case report and literature review. Journal of Infection and Chemotherapy [Internet]. 2022 May 1;28(5):663–8. Available from: https://doi.org/10.1016/j.jiac.2022.01.021
18. Willerton, L., Lucidarme, J., Walker, A., Lekshmi, A., Clark, S. A., Walsh, L., Bai, X., Lee-Jones, L., & Borrow, R. (2021). Antibiotic resistance among invasive Neisseria meningitidis isolates in England, Wales and Northern Ireland (2010/11 to 2018/19). PLoS ONE, 16(11 November). https://doi.org/10.1371/journal.pone.0260677
19. Henny Kristianti, G., Gusti Ngurah Made Suwarba, I., Sutriani Mahalini, D., Wayan Gustawan, I., & Made Gede Dwi Lingga Utama, I. (2020). Bacteria and Antibiotic Susceptibility Patterns of Cerebrospinal Fluid Isolated in Children with Bacterial Meningitis at Sanglah Hospital, Bali from 2016 to 2018. Clinical Neurology and Neuroscience, 4(3), 51. https://doi.org/10.11648/j.cnn.20200403.12
20. Kumar Bathija, S., Bano, S., & Tunio, S. A. (2024). Bacteriological Analysis And Antibiotic Resistance Trends In Bacteria Isolated From Cerebrospinal Fluid Of Suspected Bacterial Meningitis Patients At Hyderabad, Sindh. J. Biotechnol, 21(2), 387–391. https://doi.org/10.34016/pjbt.2024.21.02.922
Published
2024-12-27
Section
Article
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