Faktor Risiko Kejadian Hepatitis B Pada Ibu Hamil di Kabupaten Luwu Timur
Risk Factors for Hepatitis B Incidence in Pregnant Women in East Luwu District
Abstract
Latar Belakang: Infeksi hepatitis B (HBV) pada ibu hamil telah menjadi perhatian dunia karena penularan yang paling sering terjadi di seluruh dunia, terutama pada daerah-daerah endemis, yaitu penularan dari ibu ke anak pada masa prepartum atau perinatal dengan risiko tertular infeksi hepatitis B (HBV) pada anak lebih dari 90%.
Metode: Penelitian ini merupakan penelitian kuantitatif menggunakan metode analitik observasional dengan desain case control study. Populasi dalam penelitian ini yaitu seluruh ibu hamil yang mengikuti layanan Antenatal Care selama periode Januari – Maret 2021 di fasilitas kesehatan Kabupaten Luwu Timur. Penentuan besar sampel dengan cara “Total Sampling†untuk kelompok kasus yaitu sebanyak 50 responden dengan perbandingan kelompok kasus dan kelompok kontrol yaitu 1 : 1. Pemeriksaan HbsAg menggunakan alat Rapid Diagnostic Test (RDT). Data yang diperoleh, diolah dan dianalisis secara bivariat dengan uji chi-square dan analisis multivariat dengan uji regresi logistik menggunakan Aplikasi SPSS.
Hasil: Uji statistik menunjukkan bahwa tingkat pendidikan (p-value = 0,027; OR = 2,705; IK 95%: 1,197-6,113), paritas (p-value = 0,023; OR = 2,846; IK 95%: 1,228-6,697), dan pasangan seksual (p-value = 0,031; OR = 9,333; IK 95%: 1,121-77,704) merupakan faktor risiko kejadian hepatitis B pada ibu hamil. Sedangkan kelompok umur (p-value = 0,177) dan jenis pekerjaan (p-value = 0,059) tidak menjadi faktor risiko kejadian hepatitis B pada ibu hamil.
Kesimpulan: Tingkat pendidikan, paritas, dan pasangan seksual merupakan faktor risiko kejadian hepatitis B pada ibu hamil. Diantara semua faktor risiko yang ditemukan, pasangan seksual merupakan faktor yang paling berisiko terhadap kejadian hepatitis B pada ibu hamil di Kabupaten Luwu Timur tahun 2021 (p-value = 0,022; OR: 12,920; IK 95%: 1,440-115,894)
References
2. Amsalu A, Ferede G, Eshetie S, Tadewos A, Assegu D. Prevalence, Infectivity, and Associated Risk Factors of Hepatitis B Virus among Pregnant Women in Yirgalem Hospital, Ethiopia: Implication of Screening to Control Mother-to-Child Transmission. J Pregnancy. 2018;2018:1–9.
3. Umare A, Seyoum B, Gobena T, Mariyam TH. Hepatitis B virus infections and associated factors among pregnant women attending antenatal care clinic at deder hospital, eastern Ethiopia. PLoS One. 2016;11(11):1–11.
4. Dinkes.Lutim. Hepatitis B pada Ibu Hamil di Kabupaten Luwu Timur. Malili; 2021.
5. Badfar G, Shohani M, Nasirkandy MP, Mansouri A, Abangah G, Rahmati S, et al. Epidemiology of hepatitis B in pregnant Iranian women: a systematic review and meta-analysis. Arch Virol. 2018;163(2):319–30.
6. Balitbangkes. Situasi dan Analisis Hepatitis di Indonesia. Pusat data dan informasi Kementrian kesehatan RI. Jakarta: Kementerian Kesehatan Republik Indonesia; 2014. p. 1–8.
7. WHO. Prevention of Mother-to-Child Transmission of Hepatitis B Virus: Guidelines on Antiviral Prophylaxis in Pregnancy [Internet]. Prevention of Mother-to-Child Transmission of Hepatitis B Virus: Guidelines on Antiviral Prophylaxis in Pregnancy. 2020. 1–58 p. Available from: http://www.ncbi.nlm.nih.gov/pubmed/32833415
8. Sinaga H, Latif I, Pangulu N. Pemeriksaan Hepatitis B Surface Antigen (HBsAg) dan Anti-HBs Pada Ibu Hamil Sebagai Skrining Penularan Hepatitis B. J Ris Kesehat. 2018;7(2):81–4.
9. Anaedobe CG, Fowotade A, Omoruyi CE, Bakare RA. Prevalence, socio-demographic features and risk factors of Hepatitis B virus infection among pregnant women in Southwestern Nigeria. Pan Afr Med J. 2015;20(406):1–11.
10. Azami M, Khataee M, Beigom Bigdeli Shamloo M, Abbasalizadeh F, Rahmati S, Abbasalizadeh S, et al. Prevalence and Risk factors of hepatitis B Infection in pregnant women of Iran: a systematic review and meta-analysis. Iran J Obstet Gynecol Infertil. 2016;19(18):17–30.
11. Ngaira JAM, Kimotho J, Mirigi I, Osman S. Prevalence, awareness and risk factors associated with Hepatitis B infection among pregnant women attending the antenatal clinic at Mbagathi District Hospital in Nairobi, Kenya. Pan Afr Med J. 2016;24(315).
12. Siwi YAPE, Prijatni I, Sutrisno. Analisis Karakteristik Ibu Hamil dengan HbsAg Positif di RSUD dr. H. Koesnadi Bondowoso. Malang J Midwifery. 2020;2(1):146–54.
13. Umare A, Seyoum B, Gobena T, Haile Mariyam T. Hepatitis B virus infections and associated factors among pregnant women attending antenatal care clinic at Deder Hospital, Eastern Ethiopia. PLoS One. 2016;11(11):e0166936.
14. Metaferia Y, Dessie W, Ali I, Amsalu A. Seroprevalence and associated risk factors of hepatitis B virus among pregnant women in southern Ethiopia: a hospital-based cross-sectional study. Epidemiol Health. 2016;38(e2016027).
15. Molla S, Munshea A, Nibret E. Seroprevalence of hepatitis B surface antigen and anti HCV antibody and its associated risk factors among pregnant women attending maternity ward of Felege Hiwot Referral Hospital, northwest Ethiopia: a cross-sectional study. Virol J. 2015;12(1):1–9.
16. Kebede KM, Abateneh DD, Belay AS. Hepatitis B virus infection among pregnant women in Ethiopia: A systematic review and Meta-analysis of prevalence studies. BMC Infect Dis. 2018;18(1):1–9.
17. Hang Pham TT, Le TX, Nguyen DT, Luu CM, Truong BD, Tran PD, et al. Knowledge, attitudes and practices of hepatitis B prevention and immunization of pregnant women and mothers in northern Vietnam. PLoS One. 2019;14(4):1–15.
18. WHO. World Hepatitis Day 2019 Invest in Eliminating Hepatitis. France; 2019.
19. Manyahi J, Msigwa Y, Mhimbira F, Majigo M. High sero-prevalence of hepatitis B virus and human immunodeficiency virus infections among pregnant women attending antenatal clinic at Temeke municipal health facilities, Dar es Salaam, Tanzania: A cross sectional study. BMC Pregnancy Childbirth. 2017;17(1):1–6.
20. Tanga AT, Teshome MA, Hiko D, Fikru C, Jilo GK. Sero-prevalence of hepatitis B virus and associated factors among pregnant women in Gambella hospital, South Western Ethiopia: facility based cross-sectional study. BMC Infect Dis. 2019;19(1):1–7.
21. Magaji FA, Okolo MO, Hassan Z, Shambe IH, Pam VC, Ocheke AN, et al. Prevalence of hepatitis B virus infection among pregnant women in Jos, Nigeria. Ann Afr Med. 2020;19(3):176.
22. Liu J, Liu J, Liu M, Pang Q, Wen Y. Prevalence of hepatitis B virus infection and its associated factors among 15,461 pregnant women in Yunnan province, China. Ann Epidemiol. 2020;49:13–9.
23. Rumini, Zein U, Suroyo RB. Risk Factors Of Hepatitis B In Patient In The Dr. Pirngadi Hospital Medan. J Kesehat Glob. 2018;1(1):37–74.
24. Cetin S, Cetin M, Turhan E, Dolapcioglu K. Seroprevalence of hepatitis B surface antigen and associated risk factors among pregnant women. J Infect Dev Ctries. 2018;12(10):904–9.
25. Nguyen AT Le, Le XTT, Do TTT, Nguyen CT, Hoang Nguyen L, Tran BX, et al. Knowledge, Preference, and Willingness to Pay for Hepatitis B Vaccination Services among Woman of Reproductive Age in Vietnam. Biomed Res Int. 2019;2019.
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