Antifungal Activity of Cassia alata L. Ethyl Acetate and N-Hexane Leaves Extract against Candida albicans

  • Muhammad Anugerah Alam Waris Department of Pharmacy, Faculty of Mathematics and Science, Pancasakti University, Indonesia
  • Andi Muhammad Farid Department of Pharmacy, Faculty of Mathematics and Science, Pancasakti University, Indonesia
  • Misra Department of Pharmacy, Faculty of Mathematics and Science, Pancasakti University, Indonesia
DOI: https://doi.org/10.56338/jphp.v1i2.3714
Keywords: Cassia Alata, Antifungal, Candida Albicans

Abstract

This study aims to determine the effect of Cassia alata L. ethyl acetate and n-hexane leaves extract in inhibiting the growth of Candida albicans. The study used an experimental laboratory. In this study, C. alata ethyl acetate and n-hexane leaves extract used with concentrations of 2% w/v, 4% w/v and 8% w/v. The results showed that ethyl acetate and n-Hexane extracts inhibit C. albicans growth at 2% w/v, 4% w/v and 8% w/v concentrations with diameters of 9 mm, 11 mm, 13 mm for ethyl acetate and 9.3 mm, 12 mm, 14 mm for n-hexane solvent.

References

1. Hawkins B. Text book of gynaecology. Edisi ke-15. USA: Elsevier Publication; 2011.
2. Zubier F, Bramono K, Widaty S, Nilasari H, Louisa M, Rosana Y. Efikasi sabun ekstrak sirih merah dalam mengurangi gejala keputihan fisiologis. Maj Kedokt Indones. 2010;10.
3. Owoyale JA, Olatunji GA, Oguntoye SO. Antifungal and antibacterial activities of an alcoholic extract of Senna alata leaves. J Appl Sci Environ Manag. 2005;9(3):105–7.
4. Purba J. Pengelolaan lingkungan sosial. Yayasan Obor Indonesia; 2002.
5. Putriningrum R, Khoiriyah A, Umarianti T. Analisis Tingkat Pengetahuan Pada Ibu Hamil Trimester Iii Menuju Proses Menyusui. J Kesehat Kusuma Husada. 2015;
6. Juliantina F, Citra DA, Nirwani B, Nurmasitoh T, Bowo ET. Manfaat sirih merah (Piper crocatum) sebagai agen anti bakterial terhadap bakteri gram positif dan bakteri gram negatif. J Kedokt dan Kesehat Indones. 2009;(1):12–20.
7. Rintiswati N, Winarsih NE, Malueka RG. Potensi antikandida ekstrak madu secara in vitro dan in vivo. Berkala Ilmu Kedokteran. 2004;36(2004).
8. Hariana HA. Tumbuhan Obat & Khasiatnya 3. Niaga Swadaya; 2008.
9. Ariyanti NK, Darmayasa IBG, Sudirga SK. Daya hambat ekstrak kulit daun lidah buaya (Aloe barbadensis Miller) terhadap pertumbuhan bakteri Staphylococcus aureus ATCC 25923 dan Escherichia coli ATCC 25922. J Biol. 2012;16(1):1–4.
10. Kurniawati A, Mashartini A, Fauzia IS. Perbedaan khasiat anti jamur antara ekstrak etanol daun Kersen (Muntingia calabura L.) dengan nistatin terhadap pertumbuhan Candida albicans. 2016;
11. Ermayanti A. Pengaruh Pemberian Profilaksis Nistatin Terhadap Kandidiasis Oral Pada Neonatus Di HCU Neonatus. UNS (Sebelas Maret University); 2014.
Published
2021-07-25
How to Cite
Muhammad Anugerah Alam Waris, Andi Muhammad Farid, & Misra. (2021). Antifungal Activity of Cassia alata L. Ethyl Acetate and N-Hexane Leaves Extract against Candida albicans . Journal of Public Health and Pharmacy, 1(2), 27-29. https://doi.org/10.56338/jphp.v1i2.3714
Issue
Vol. 1 No. 2: JULY 2021
Section
Articles

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