Antifungal Activity of Cassia alata L. Ethyl Acetate and N-Hexane Leaves Extract against Candida albicans
Abstract
This study aims to determine the effect of Cassia alata L. ethyl acetate and n-hexane leaves extract in inhibiting the growth of Candida albicans. The study used an experimental laboratory. In this study, C. alata ethyl acetate and n-hexane leaves extract used with concentrations of 2% w/v, 4% w/v and 8% w/v. The results showed that ethyl acetate and n-Hexane extracts inhibit C. albicans growth at 2% w/v, 4% w/v and 8% w/v concentrations with diameters of 9 mm, 11 mm, 13 mm for ethyl acetate and 9.3 mm, 12 mm, 14 mm for n-hexane solvent.
References
2. Zubier F, Bramono K, Widaty S, Nilasari H, Louisa M, Rosana Y. Efikasi sabun ekstrak sirih merah dalam mengurangi gejala keputihan fisiologis. Maj Kedokt Indones. 2010;10.
3. Owoyale JA, Olatunji GA, Oguntoye SO. Antifungal and antibacterial activities of an alcoholic extract of Senna alata leaves. J Appl Sci Environ Manag. 2005;9(3):105–7.
4. Purba J. Pengelolaan lingkungan sosial. Yayasan Obor Indonesia; 2002.
5. Putriningrum R, Khoiriyah A, Umarianti T. Analisis Tingkat Pengetahuan Pada Ibu Hamil Trimester Iii Menuju Proses Menyusui. J Kesehat Kusuma Husada. 2015;
6. Juliantina F, Citra DA, Nirwani B, Nurmasitoh T, Bowo ET. Manfaat sirih merah (Piper crocatum) sebagai agen anti bakterial terhadap bakteri gram positif dan bakteri gram negatif. J Kedokt dan Kesehat Indones. 2009;(1):12–20.
7. Rintiswati N, Winarsih NE, Malueka RG. Potensi antikandida ekstrak madu secara in vitro dan in vivo. Berkala Ilmu Kedokteran. 2004;36(2004).
8. Hariana HA. Tumbuhan Obat & Khasiatnya 3. Niaga Swadaya; 2008.
9. Ariyanti NK, Darmayasa IBG, Sudirga SK. Daya hambat ekstrak kulit daun lidah buaya (Aloe barbadensis Miller) terhadap pertumbuhan bakteri Staphylococcus aureus ATCC 25923 dan Escherichia coli ATCC 25922. J Biol. 2012;16(1):1–4.
10. Kurniawati A, Mashartini A, Fauzia IS. Perbedaan khasiat anti jamur antara ekstrak etanol daun Kersen (Muntingia calabura L.) dengan nistatin terhadap pertumbuhan Candida albicans. 2016;
11. Ermayanti A. Pengaruh Pemberian Profilaksis Nistatin Terhadap Kandidiasis Oral Pada Neonatus Di HCU Neonatus. UNS (Sebelas Maret University); 2014.
Journal of Public Health and Pharmacy has CC-BY-SA or an equivalent license as the optimal license for the publication, distribution, use, and reuse of scholarly work. Authors who publish with this journal retain copyright and grant the journal the right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike 4.0 International License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.