The Relationship Between PM2.5 and Indoor TVOCs Exposure, Physical Environmental Factors, and Atopy History and allergic Asthma Complaints in 13-14 Years old Children at a Full-Day School in Surabaya

  • I Dewa Gede Deva Pradnyana Putra Department of Environmental Health, Faculty of Public Health, Airlangga University, Surabaya
  • Megara Maritza Tabina Department of Environmental Health, Faculty of Public Health, Airlangga University, Surabaya
  • Winarko Department of Environmental Health, Poltekkes Kemenkes Surabaya, Indonesia
Keywords: Allergic Asthma Complaints, Atopic History, Indoor Air Quality, School

Abstract

Introduction: Indoor air pollutants can cause respiratory irritants and trigger allergic asthma complaints, especially in children with a history of atopy. Previous research has found that air pollutants, including PM2.5 and TVOCs, pose risks to respiratory allergy complaints in children. Children spend a significant amount of time at school, so the air quality in classrooms affects their health and productivity. The study was conducted at SMPN 19 Surabaya, located alongside a major road and with a variety of classroom types, potentially exacerbating asthma complaints in children. The research aimed to identify the relationship between exposure to PM2.5, TVOCs, physical environmental factors, and atopy history with asthma complaints in 13-14-year-old children at SMPN 19 Surabaya.

Objective: The study aimed to identify the relationship between exposure to PM2.5, TVOCs, physical environmental factors, and atopy history with asthma complaints in 13-14-year-old children at SMPN 19 Surabaya.

Method: The research was a quantitative study with an analytical observational design using a cross-sectional approach. The sample size for the study was 69 students aged 13-14 years, selected through purposive sampling from two different characteristic classes, at SMPN 19 Surabaya. An air quality detector was used to measure PM2.5, TVOCs, temperature, and humidity in both classes as well as observe the class's physical condition. Data was collected from student interviews using the ISAAC questionnaire. Data analysis used a bivariate test.

Result: The research results showed a relationship between a history of atopy and allergic asthma complaints in children aged 13-14 years in classes 7G and 8A at SMPN 19 Surabaya (p=0.000) and (OR=23.368). However, for indoor pollutant levels PM2.5 (OR= 1.710), TVOCs (OR=1.710), and physical environmental factors such as temperature and humidity did not show a relationship with allergic asthma complaints.

Conclusion: It can be concluded that a family history of atopy is associated with asthma complaints in classes at SMPN 19 Surabaya. Therefore, increased awareness and supervision of children with a history of atopy are necessary to prevent or manage potential asthma complaints.

References

Dewi WC, Raharjo M, Wahyuningsih NE. Literatur Review : Hubungan Antara Kualitas Udara Ruang

Dengan Gangguan Kesehatan Pada Pekerja. An-Nadaa J Kesehat Masy. 2021;8(1):88.

Becerril-Ángeles M, Vargas MH, Medina-Reyes IS, Rascón-Pacheco RA. Trends (2007–2019) of major

atopic diseases throughout the life span in a large Mexican population. World Allergy Organ J [Internet].

;16(1):100732. Available from: https://doi.org/10.1016/j.waojou.2022.100732

Paciência I, Cavaleiro Rufo J. Urban-level environmental factors related to pediatric asthma. Porto Biomed

J. 2020;5(1):e57.

Abdel-Salam MMM. Assessment of children’s exposure to air pollutants in urban residences during the

COVID-19 pandemic. Front Environ Sci. 2022;10(October):1–16.

Anake WU, Nnamani EA. Indoor air quality in day-care centres: a global review. Air Qual Atmos Heal

[Internet]. 2023;16(5):997–1022. Available from: https://doi.org/10.1007/s11869-023-01320-5

Vornanen-Winqvist C, Salonen H, Järvi K, Andersson MA, Mikkola R, Marik T, et al. Effects of ventilation

improvement on measured and perceived indoor air quality in a school building with a hybrid ventilation

system. Int J Environ Res Public Health. 2018;15(7):1–18.

Haryanto B, Resosoedarmo B, Utami STB, Hartono B, Hermawati E. Effect of Ambient Particulate Matter

5 Micrometer (PM2.5) to Prevalence of Impaired Lung Function and Asthma in Tangerang and Makassar.

Kesmas Natl Public Heal J. 2016;10(4):145.

Khalili R, Bartell SM, Hu X, Liu Y, Chang HH, Belanoff C, et al. Early-life exposure to PM2.5 and risk of

acute asthma clinical encounters among children in Massachusetts: A case-crossover analysis. Environ Heal

A Glob Access Sci Source. 2018;17(1):1–9.

Nur RA, Suwondo A, Jayanti S, Keselamatan B, Masyarakat FK. Hubungan Paparan Debu Pm2.5Terhadap

Gangguan Fungsi Paru Pada Pengemudi Bus Rapid Transit(Brt) Semarang. J Kesehat Masy. 2019;7(3):140–

Zhou J, Lei R, Xu J, Peng L, Ye X, Yang D, et al. The Effects of Short-Term PM2.5 Exposure on

Pulmonary Function among Children with Asthma—A Panel Study in Shanghai, China. Int J Environ Res

Public Health. 2022;19(18).

Qian L, Mehrabi Nasab E, Athari SM, Athari SS. Mitochondria Signaling Pathways in Allergic Asthma. J

Investig Med. 2022;70(4):863–82.

Momtazmanesh S, Moghaddam SS, Ghamari SH, Rad EM, Rezaei N, Shobeiri P, et al. Global burden of

chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease

Study 2019. eClinicalMedicine. 2023;59(10).

Nurmatov UB, Tagiyeva N, Semple S, Devereux G, Sheikh A. Volatile Organic Compounds and Risk of

Asthma and Allergy: A Systematic Review. Eur Respir Rev. 2015;24(135):92–101.

Kurniawati AD. Dengan Kejadian Serangan Asma Anak Di Kota Semarang 2005 Program Pascasarjana

Universitas Diponegoro Semarang. 2006;

Gostner JM, Zeisler J, Alam MT, Gruber P, Fuchs D, Becker K, et al. Cellular reactions to long-term

volatile organic compound (VOC) exposures. Sci Rep [Internet]. 2016;6(December 2016):1–14. Available

from: http://dx.doi.org/10.1038/srep37842

Kwon JW, Park HW, Kim WJ, Kim MG, Lee SJ. Exposure To Volatile Organic Compounds And Airway

Inflammation. Environ Heal A Glob Access Sci Source. 2018;17(1):1–8.

Kahar K, Karmini M, Kamaludin A. Ekstrak Lidah Mertua (Sansevieria sp.) Efektif dalam Mereduksi

Volatile Organic Compound (VOC)-Benzena Dalam Ruang. J Kesehat Lingkung J dan Apl Tek Kesehat

Lingkung. 2022;19(1):1–6.

Zhong L, Su FC, Batterman S. Volatile Organic Compounds (VOCs) in Conventional and High

Performance School Buildings in the U.S. Int J Environ Res Public Health. 2017;14(1).

Zauli-Sajani S, Marchesi S, Boselli G, Broglia E, Angella A, Maestri E, et al. Effectiveness of a Protocol to

Reduce Children’s Exposure to Particulate Matter and NO2 in Schools during Alert Days. Int J Environ Res

Public Health. 2022;19(17).

Lim CL. Fundamental concepts of human thermoregulation and adaptation to heat: A review in the context

of global warming. Int J Environ Res Public Health. 2020;17(21):1–33.

Chipps BE, Soong W, Panettieri RA, Carr W, Gandhi H, Zhou W, et al. Number of patient-reported asthma

triggers predicts uncontrolled disease among specialist-treated patients with severe asthma. Ann Allergy,

Asthma Immunol. 2023;130(6):784-790.e5.

Wei Y, Dong Z, Fan W, Xu K, Tang S, Wang Y, et al. A narrative review on the role of temperature and

humidity in COVID-19: Transmission, persistence, and epidemiological evidence. Eco-Environment Heal.

;1(2):73–85.

Fan Y, Wang J, Obradovich N, Zheng S. Intraday adaptation to extreme temperatures in outdoor activity.

Sci Rep. 2023;13(1):1–11.

He L, Evans S, Norris C, Barkjohn K, Cui X, Li Z, et al. Associations between personal apparent

temperature exposures and asthma symptoms in children with asthma. PLoS One [Internet]. 2023;18(11

November):1–14. Available from: http://dx.doi.org/10.1371/journal.pone.0293603

Yaneva M, Darlenski R. The link between atopic dermatitis and asthma- immunological imbalance and

beyond. Asthma Res Pract. 2021;7(1):1–8.

Chu DK, Schneider L, Asiniwasis RN, Boguniewicz M, De Benedetto A, Ellison K, et al. Atopic dermatitis

(eczema) guidelines: 2023 American Academy of Allergy, Asthma and Immunology/American College of

Allergy, Asthma and Immunology Joint Task Force on Practice Parameters GRADE– and Institute of

Medicine–based recommendations. Ann Allergy, Asthma Immunol [Internet]. 2024;132(3):274–312.

Available from: https://doi.org/10.1016/j.anai.2023.11.009

Venter C, Palumbo MP, Sauder KA, Glueck DH, Liu AH, Yang I V., et al. Incidence and timing of

offspring asthma, wheeze, allergic rhinitis, atopic dermatitis, and food allergy and association with maternal

history of asthma and allergic rhinitis. World Allergy Organ J. 2021;14(3):100526.

O’Connor C, Livingstone V, Hourihane JOB, Irvine AD, Boylan G, Murray D. Parental atopy and risk of

atopic dermatitis in the first two years of life in the BASELINE birth cohort study. Pediatr Dermatol.

;39(6):896–902.

Kansen HM, Le TM, Uiterwaal CSPM, van Ewijk BE, Balemans WAF, Gorissen DMW, et al. Prevalence

and predictors of uncontrolled asthma in children referred for asthma and other atopic diseases. J Asthma

Allergy. 2020;13:67–75.

Published
2024-08-12
How to Cite
Pradnyana Putra, I. D. G. D., Megara Maritza Tabina, & Winarko. (2024). The Relationship Between PM2.5 and Indoor TVOCs Exposure, Physical Environmental Factors, and Atopy History and allergic Asthma Complaints in 13-14 Years old Children at a Full-Day School in Surabaya. Media Publikasi Promosi Kesehatan Indonesia (MPPKI), 7(8), 2098-2108. https://doi.org/10.56338/mppki.v7i8.5537