Shift Work and Metabolic Syndrome: Systematic Review
Abstract
Introduction: Compared to standard working hours, shift work is one of the most popular options. The disruption of circadian rhythms caused by shift work and the loss of circadian rhythms caused by sleep disturbances are considered to be major risk factors for the development of metabolic diseases.
Objective: This systematic review analyzed the relationship of shift work to the risk of metabolic syndrome
Method: Systematic searches using pubmed, scopus, proquest, science direct and google scholar were published within 2014 - 2024 using English and Indonesian. Reviews are displayed in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 and article quality assessment using the PICO framework (Patient/Population, Intervention, Comparator/Control, and Outcome).
Result: 9 out of 10 articles show that shift workers have a higher incidence of metabolic syndrome and most studies show the effect of shift work on several indicators of metabolic syndrome.
Conclusion: There is an association between shift work (night work or rotating shifts) and various metabolic syndrome disorders. Circadian misalignment due to night work activities can cause systemic metabolic dysfunction
References
International Labour Organization (ILO). Conditions of Work and Employment Programme Working time in the twenty-first century. First. Geneva: TWEWTA; 2011.
International Labour Organization (ILO). Working Time and Work-Life Balance Around the World. First. Geneva: International Labour Organization; 2022. 52–53 p.
International Labour Organization (ILO). Ensuring decent working time for the future. Report III. Geneva: International Labour Organization; 2018.
National Health Interview Survey (NHIS). Work Organization Characteristics (NHIS 2015) Charts [Internet]. NIOSH Worker Health Charts. U.S; 2015. Available from: https://wwwn.cdc.gov/NIOSH-WHC/chart/ohs-workorg/work?OU=*&T=OU&V=R
Eurofound, International Labour Organization (ILO). Working conditions in a global perspective. Geneva; 2019.
Alice M, Schettini S. Shift Work and Metabolic Syndrome Updates?: A Systematic Review. Brazilian Sleep Assoc [Internet]. 2023;16(2). Available from: https://doi.org/ 10.1055/s-0043-1770798
Mohamed SM, Shalaby MA, El-shiekh RA. Metabolic syndrome?: risk factors, diagnosis, pathogenesis, and management with natural approaches Metabolic syndrome?: risk factors, diagnosis, pathogenesis, and management with natural approaches. Food Chem Adv [Internet]. 2023;3(December). Available from: https://doi.org/10.1016/j.focha.2023.100335
American Heart Association. 2022 Heart Disease & Stroke Statistical Update Fact Sheet Global Burden of Disease [Internet]. 2022. Available from: https://www.ahajournals.org/doi/10.1161/CIR.0000000000001052%0AIf
Hermansson J, Bøggild H, Hallqvist J, Karlsson B, Knutsson A, Nilsson T, et al. Interaction between Shift Work and Established Coronary Risk Factors. Int J Occup Env Med [Internet]. 2019;10(2):57–65. Available from: doi: 10.15171/ijoem.2019.1466
Hosseini M. Formulating Research Questions for Evidence-Based Studies Journal of Medicine , Surgery, and Public Health Formulating research questions for evidence-based studies Yosra Vaez-Gharamaleki. J Med Surgery, Public Heal [Internet]. 2023;2(December):100046. Available from: https://doi.org/10.1016/j.glmedi.2023.100046
Page MJ, Mckenzie JE, Bossuyt PM, Boutron I, Hoffmann C, Mulrow CD, et al. The PRISMA 2020 statement?: an updated guideline for reporting systematic reviews Systematic reviews and Meta-Analyses. BMJ [Internet]. 2021; Available from: http://dx.doi.org/10.1136/bmj.n71
International Labour Organization (ILO). Guide to Developing Balanced Working Time Arrangements. Geneva: International Labour Office; 2019. 13–15 p.
Satphati T, Unnikrishnan R, Mohan V. Metabolic Syndrom From Mechanisms to Intervention. Mukhopadhyay S, Mondal S, editors. Elsevier Inc.; 2024. 35 p.
World Health Organization (WHO). Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications Part 1: Diagnosis and Classification of Diabetes Mellitus [Internet]. Geneva: World Health Organization; 1999. Available from: https://iris.who.int/handle/10665/66040
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection Evaluation and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. JAMA [Internet]. 2001;285(19):2486–2497. Available from: doi: 10.1001/jama.285.19.2486
Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. AHA / NHLBI Scientific Statement Diagnosis and Management of the Metabolic Syndrome An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Am Hear Assoc [Internet]. 2005;2735–52. Available from: doi: 10.1161/CIRCULATIONAHA.105.169404
International Diabetes Federation. The IDF Consensus Worldwide Definition of The Metabolic Syndrome [Internet]. IDF Communications; 2006. Available from: www.idf.org
Alberti KGMM, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International . Circulation [Internet]. 2009 Oct;120(16):1640–5. Available from: 10.1161/CIRCULATIONAHA.109.192644
Ye B. Association between Shift Work and Metabolic Syndrome?: A 4-Year Retrospective Cohort Study. Healthcare [Internet]. 2023;11(802). Available from: https://doi.org/10.3390/healthcare 11060802
Khosravipour M, Shahmohammadi M, Valadi H. Diabetes & Metabolic Syndrome?: Clinical Research & Reviews The effects of rotating and extended night shift work on the prevalence of metabolic syndrome and its components. Diabetes Metab Syndr Clin Res Rev [Internet]. 2019;13(6):3085–9. Available from: https://doi.org/10.1016/j.dsx.2019.11.006
Dong C, Zeng H, Yang B, Zhang Y, Li Z. The association between long ? term night shift work and metabolic syndrome?: a cross ? sectional study of male railway workers in southwest China. BMC Cardiovasc Disord [Internet]. 2022;22263:1–7. Available from: https://doi.org/10.1186/s12872-022-02705-7
Guo Y, Rong Y, Huang X, Lai H, Luo X, Zhang Z. Shift Work and the Relationship with Metabolic Syndrome in Chinese Aged Workers. PLoS One [Internet]. 2015;10(3):1–12. Available from: doi:10.1371/journal.pone.0120632
Cheng W, Liu C, Hu K, Cheng Y, Karhula K. Night shift work and the risk of metabolic syndrome?: Findings from an 8-year hospital cohort. PLoS One [Internet]. 2021;16(12):1–10. Available from: https://doi.org/10.1371/journal. pone.0261349
Gowda RH, Melur G, Gowda SH. Association between metabolic risk , oxidative stress and rotating shift work in a tertiary health care facility. Clin Epidemiol Glob Heal [Internet]. 2019;7(4):564–70. Available from: https://doi.org/10.1016/j.cegh.2019.01.002
Korsiak J, Tranmer J, Day A, Aronson KJ. Sleep duration as a mediator between an alternating day and night shift work schedule and metabolic syndrome among female hospital employees. BMJ [Internet]. 2017;1–7. Available from: http://dx.doi.org/10.1136/oemed-2017-104371
Kumar SE, Antonisamy B, Kirupakaran H, Alex RG. A Cross-sectional study among Hospital Employees- Metabolic Syndrome and Shift Work. Indones J Occup Saf Heal [Internet]. 2021;10(2):258–64. Available from: http://dx.doi.org/10.1136/oemed-2017-104371
Lim YC, Hoe VCW, Darus A, Bhoo-pathy N. Association between night-shift work , sleep quality and metabolic syndrome. BMJ [Internet]. 2018;1–8. Available from: 10.1136/oemed-2018-105104
Oh J, Yim HW. Association between rotating night shift work and metabolic syndrome in Korean workers?: differences between 8-hour and 12-hour rotating shift work. Ind Health [Internet]. 2018;56:40–8. Available from: doi: 10.2486/indhealth.2017-0072
Shimizu I, Yoshida Y, Minamino T. A role for circadian clock in metabolic disease. Hypertens Res [Internet]. 2016;39(January):483–91. Available from: doi:10.1038/hr.2016.12
Boivin DB, Boudreau P, Kosmadopoulos A. Disturbance of the Circadian System in Shift Work and Its Health Impact. J Biol Rhythms [Internet]. 2022;3–28. Available from: https://doi.org/10.1177/07487304211064218
Boege HL, Bhatti MZ. Circadian rhythms and meal timing?: impact on energy balance and body weight. ScienceDirect [Internet]. 2021;70:1–6. Available from: https://doi.org/10.1016/j.copbio.2020.08.009
Chaput J, Mchill AW, Broussard JL, Dutil C, Costa BGG. The role of insufficient sleep and circadian misalignment in obesity. Nature [Internet]. 2023;19(February). Available from: https://doi.org/10.1038/ s41574-022-00747-7
Dorrian J, Heath G, Sargent C, Banks S, Coates A. Alcohol use in shiftworkers. Accid Anal Prev [Internet]. 2017;99:395–400. Available from: http://dx.doi.org/10.1016/j.aap.2015.11.011 0001-4575/
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