Faktor Risiko Penyakit Ginjal Kronis pada Kelompok Usia Dewasa : Literature Review
Risk Factors for Chronic Kidney Disease in the Adult Age Group : Literature Review
Abstract
Latar Belakang: Penyakit ginjal kronis adalah salah satu penyakit katastropik yang menjadi beban pembiayaan kesehatan. Perlunya mengetahui faktor risiko penyakit ini dapat menjadi salah satu upaya awal dalam pencegahan penyakit ginjal kronis.
Tujuan: Penelitian ini untuk menganalisis literatur ilmiah yang membahas faktor risiko gagal ginjal kronis pada usia dewasa.
Metode: Systematic review digunakan sebagai metode dalam penelitian ini. Artikel yang digunakan adalah artikel berbahasa inggris dengan rentang waktu tahun 2012-2022 yang didapat dari database Scopus, ScienceDirect dan ProQuest. Kriteria inklusi yaitu data-data yang memuat kata kunci faktor risiko, ginjal kronis, dan dewasa, sedangkan kriteria eksklusi adalah artikel yang tidak berhubungan dengan kata kunci tersebut. Artikel yang disertakan pada penelitian ini adalah desain cross-sectional dengan jumlah sampel yang besar dan dilakukan di berbagai negara seperti Nikaragua, Amerika Serikat, Ethiopia, Nepal, Malaysia, Nigeria, Iran, India dan Cina.
Hasil: Diperoleh 10 artikel yang membahas faktor risiko penyakit ginjal kronis pada usia dewasa. Sebagian besar faktor risiko yang dibahas adalah usia, jenis kelamin, etnis, riwayat keluarga dengan penyakit ginjal, hipertensi, diabetes melitus, batu ginjal, obesitas, dislipidemia, dan merokok.
Kesimpulan: Faktor yang meningkatkan risiko penyakit ginjal kronis adalah individu dengan usia yang lebih tua, laki-laki, etnis tertentu (Afrika Amerika, Hispanik, Amerika Asli, atau Asia), memiliki riwayat penyakit ginjal keluarga, hipertensi, diabetes melitus, batu ginjal, obesitas, hiperkolesterolemia, dan merokok. Memahami faktor penyebab dan menerapkan skrining pada populasi yang berisiko akan meningkatkan deteksi dini, memulai pengobatan faktor risiko yang dapat dimodifikasi, dan pengobatan yang tepat untuk PGK. Pencegahan dapat dilakukan melalui kegiatan promotif dan preventif untuk mengurangi kasus penyakit ginjal kronis di masyarakat, yaitu dengan menerapkan gaya hidup sehat.
References
Pusat Data dan Informasi Kementerian Kesehatan RI. Situasi Penyakit Ginjal Kronis [Internet]. Kementerian Kesehatan RI. 2017. Available from: https://www.kemkes.go.id/article/view/17050400001/situasi-penyakit-ginjal-kronis-.html.
Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2011). Elsevier B.V.; 2022. p. 7–11.
Bikbov B, Purcell CA, Levey AS, Smith M, Abdoli A, Abebe M, Adebayo OM, Afarideh M, Agarwal SK, Agudelo-Botero M, et al. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 2020;395:709–733. doi: 10.1016/S0140-6736(20)30045-3. Cited: in: : PMID: 32061315.
Kemenkes RI. Laporan Nasional Riskesdas 2018. Balitbang Kemenkes RI. 2018; Cited: in: : PMID: 25246403.
Kazancioǧlu R. Risk factors for chronic kidney disease: An update. Kidney Int Suppl (2011). Nature Publishing Group; 2013. p. 368–371.
Jonsson AJ, Lund SH, Eriksen BO, Palsson R, Indridason OS. Incidence of and risk factors of chronic kidney disease: Results of a nationwide study in Iceland. Clin Kidney J. 2022;15:1290–1299. doi: 10.1093/ckj/sfac051.
Centers for Disease Control and Prevention. CKD Risk Factors and Prevention [Internet]. Centers for Disease Control and Prevention. 2022 [cited 2023 Feb 21]. Available from: https://www.cdc.gov/kidneydisease/publications-resources/annual-report/ckd-risk-prevention.html#:~:text=Diabetes%20and%20high%20blood%20pressure,can%20help%20keep%20kidneys%20healthy.
Tsai WC, Wu HY, Peng Y sen, Ko MJ, Wu MS, Hung KY, Wu KD, Chu TS, Chien KL. Risk factors for development and progression of chronic kidney disease: A systematic review and exploratory meta-analysis. Medicine (United States). 2016;95. doi: 10.1097/MD.0000000000003013. Cited: in: : PMID: 26986114.
Nazzal Z, Hamdan Z, Masri D, Abu-Kaf O, Hamad M. Prevalence and risk factors of chronic kidney disease among Palestinian type 2 diabetic patients: a cross-sectional study. BMC Nephrol. 2020;21. doi: 10.1186/s12882-020-02138-4. Cited: in: : PMID: 33198669.
He G, Li C, Zhong X, Wang F, Wang H, Shi Y, Gan L, Ding J. Risk Factors for Progression of Chronic Kidney Disease With Glomerular Etiology in Hospitalized Children. Front Pediatr. 2021;9. doi: 10.3389/fped.2021.752717.
Delanaye P, Jager KJ, Bökenkamp A, Christensson A, Dubourg L, Eriksen BO, Gaillard F, Gambaro G, van der Giet M, Glassock RJ, et al. CKD: A call for an age-adapted definition. Journal of the American Society of Nephrology. American Society of Nephrology; 2019. p. 1785–1805.
Ariyanto, Hadisaputri S, Lestariningsih, Adi S, Budijitno S. Beberapa Faktor Risiko Kejadian Penyakit Ginjal Kronik (PGK) Stadium V pada Kelompok Usia Kurang dari 50 Tahun (Studi di RSUD dr. H. Soewondo Kendal dan RSUD dr. Adhyatma Semarang). Jurnal Epidemiologi Kesehatan Komunitas. 2018;3:1–6.
Badan Pusat Statistik. Jumlah Penduduk Menurut Kelompok Umur dan Jenis Kelamin [Internet]. BPS. 2022. Available from: https://www.bps.go.id/indikator/indikator/view_data_pub/0000/api_pub/YW40a21pdTU1cnJxOGt6dm43ZEdoZz09/da_03/1.
Canêo LF, Neirotti R. The importance of the proper definition of adulthood: What is and what is not included in a scientific publication. Braz J Cardiovasc Surg. Sociedade Brasileira de Cirurgia Cardiovascular; 2017. p. 60–61.
Lebov JF, Valladares E, Peña R, Peña EM, Sanoff SL, Cisneros EC, Colindres RE, Morgan DR, Hogan SL. A population-based study of prevalence and risk factors of chronic kidney disease in León, Nicaragua. Can J Kidney Health Dis. 2015;2. doi: 10.1186/s40697-015-0041-1. Cited: in: : PMID: 25926994.
Lin J-J, Morey F, Wu H-Y, Yang J-Y, Peng Y-S, Mendez D, Chebat M. Prevalence and Risk Factors for Chronic Kidney Disease in Belize: A Population-based Survey. The Lancet Regional Health - Americas [Internet]. 2021;1:100013. doi: 10.1016/j.lana.2021.10.
Hussien FM, Hassen HY. Dietary habit and other risk factors of chronic kidney disease among patients attending dessie referral hospital, northeast Ethiopia. Int J Nephrol Renovasc Dis. 2020;13:119–127. doi: 10.2147/IJNRD.S248075.
Poudyal A, Karki KB, Shrestha N, Aryal KK, Mahato NK, Bista B, Ghimire L, Dirghayu KC, Gyanwali P, Jha AK, et al. Prevalence and risk factors associated with chronic kidney disease in Nepal: Evidence from a nationally representative population-based cross-sectional study. BMJ Open. 2022;12. doi: 10.1136/bmjopen-2021-057509. Cited: in: : PMID: 35314475.
Saminathan TA, Hooi LS, Mohd Yusoff MF, Ong LM, Bavanandan S, Rodzlan Hasani WS, Tan EZZ, Wong I, Rifin HM, Robert TG, et al. Prevalence of chronic kidney disease and its associated factors in Malaysia; Findings from a nationwide population-based cross-sectional study. BMC Nephrol. 2020;21. doi: 10.1186/s12882-020-01966-8. Cited: in: : PMID: 32795256.
Olanrewaju TO, Aderibigbe A, Popoola AA, Braimoh KT, Buhari MO, Adedoyin OT, Kuranga SA, Biliaminu SA, Chijioke A, Ajape AA, et al. Prevalence of chronic kidney disease and risk factors in North-Central Nigeria: a population-based survey. BMC Nephrol. 2020;21. doi: 10.1186/s12882-020-02126-8. Cited: in: : PMID: 33167899.
Dehghani A, Alishavandi S, Nourimajalan N, Fallahzadeh H, Rahmanian V. Prevalence of chronic kidney diseases and its determinants among Iranian adults: results of the first phase of Shahedieh cohort study. BMC Nephrol. 2022;23. doi: 10.1186/s12882-022-02832-5. Cited: in: : PMID: 35681145.
Xue L, Lou Y, Feng X, Wang C, Ran Z, Zhang X. Prevalence of chronic kidney disease and associated factors among the Chinese population in Taian, China Epidemiology and Health Outcomes. BMC Nephrol. 2014;15. doi: 10.1186/1471-2369-15-205. Cited: in: : PMID: 24559433.
Okwuonu CG, Chukwuonye II, Adejumo OA, Agaba EI, Ojogwu LI. Prevalence of chronic kidney disease and its risk factors among adults in a semi-urban community of South-East Nigeria. Niger Postgrad Med J. 2017;24:81–87. doi: 10.4103/npmj.npmj_34_17. Cited: in: : PMID: 28762361.
Anupama YJ, Uma G. revalence of chronic kidney disease among adults in a rural community in South India: Results from the kidney disease screening (KIDS) project. Indian J Nephrol [Internet]. 2014;24. doi: doi: 10.4103/0971-4065.132990.
Liu P, Quinn RR, Lam NN, Elliott MJ, Xu Y, James MT, Manns B, Ravani P. Accounting for Age in the Definition of Chronic Kidney Disease. JAMA Intern Med. 2021;181:1359–1366. doi: 10.1001/jamainternmed.2021.4813. Cited: in: : PMID: 34459844.
Prakash S, O’Hare AM. Interaction of Aging and Chronic Kidney Disease. Semin Nephrol. 2009;29:497–503. doi: 10.1016/j.semnephrol.2009.06.006. Cited: in: : PMID: 19751895.
Palit S, Kendrick J. Vascular Calcification in Chronic Kidney Disease: Role of Disordered Mineral Metabolism. Curr Pharm Des. 2014;20:5829–5883.
Fang Y, Gong AY, Haller ST, Dworkin LD, Liu Z, Gong R. The ageing kidney: Molecular mechanisms and clinical implications. Ageing Res Rev. Elsevier Ireland Ltd; 2020.
Hounkpatin HO, Fraser SDS, Honney R, Dreyer G, Brettle A, Roderick PJ. Ethnic minority disparities in progression and mortality of pre-dialysis chronic kidney disease: A systematic scoping review. BMC Nephrol. BioMed Central Ltd; 2020.
Ulasi II, Tzur S, Wasser WG, Shemer R, Kruzel E, Feigin E, Ijoma CK, Onodugo OD, Okoye JU, Arodiwe EB, et al. High Population Frequencies of APOL1 Risk Variants Are Associated with Increased Prevalence of Non-Diabetic Chronic Kidney Disease in the Igbo People from South-Eastern Nigeria. Nephron Clin Pract. 2013;123:123–128. doi: 10.1159/000353223.
Pugh D, Gallacher PJ, Dhaun N. Management of Hypertension in Chronic Kidney Disease. Drugs. 2019;79:365–379. doi: 10.1007/s40265-019-1064-1. Cited: in: : PMID: 30758803.
Lee H, Kwon SH, Jeon JS, Noh H, Han DC, Kim H. Association between blood pressure and the risk of chronic kidney disease in treatment-naïve hypertensive patients. Kidney Res Clin Pract. 2022;41:31–42. doi: 10.23876/j.krcp.21.099.
Bidani AK, Griffin KA. Pathophysiology of hypertensive renal damage: Implications for therapy. Hypertension. 2004. p. 595–601.
Jitraknatee J, Ruengorn C, Nochaiwong S. Prevalence and Risk Factors of Chronic Kidney Disease among Type 2 Diabetes Patients: A Cross-Sectional Study in Primary Care Practice. Sci Rep. 2020;10. doi: 10.1038/s41598-020-63443-4. Cited: in: : PMID: 32277150.
Sigurjonsdottir VK, Runolfsdottir HL, Indridason OS, Palsson R, Edvardsson VO. Impact of nephrolithiasis on kidney function. BMC Nephrol. 2015;16. doi: 10.1186/s12882-015-0126-1. Cited: in: : PMID: 26316205.
Rule AD, Bergstralh EJ, Melton LJ, Li X, Weaver AL, Lieske JC. Kidney stones and the risk for chronic kidney disease. Clinical Journal of the American Society of Nephrology. 2009;4:804–811. doi: 10.2215/CJN.05811108. Cited: in: : PMID: 19339425.
Keller JJ, Chen YK, Lin HC. Association between chronic kidney disease and urinary calculus by stone location: A population-based study. BJU Int. 2012;110. doi: 10.1111/j.1464-410X.2012.11380.x. Cited: in: : PMID: 22934937.
Kovesdy CP, Furth SL, Zoccali C. Obesity and kidney disease: hidden consequences of the epidemic. J Nephrol. Springer New York LLC; 2017.
Kwakernaak AJ, Zelle DM, Bakker SJL, Navis G. Central body fat distribution associates with unfavorable renal hemodynamics independent of body mass index. Journal of the American Society of Nephrology. 2013;24:987–994. doi: 10.1681/ASN.2012050460. Cited: in: : PMID: 23578944.
Liang X, Ye M, Tao M, Zheng D, Cai R, Zhu Y, Jin J, He Q. The association between dyslipidemia and the incidence of chronic kidney disease in the general Zhejiang population: A retrospective study. BMC Nephrol. 2020;21. doi: 10.1186/s12882-020-01907-5. Cited: in: : PMID: 32616008.
Samuel VT, Shulman GI. Mechanisms for insulin resistance: Common threads and missing links. Cell. Elsevier B.V.; 2012. p. 852–871.
Orth SR, Hallan SI. Smoking: A risk factor for progression of chronic kidney disease and for cardiovascular morbidity and mortality in renal patients - Absence of evidence or evidence of absence? Clinical Journal of the American Society of Nephrology. 2008. p. 226–236.
Choi HS, Han K do, Oh TR, Kim CS, Bae EH, Ma SK, Kim SW. Smoking and risk of incident end-stage kidney disease in general population: A Nationwide Population-based Cohort Study from Korea. Sci Rep. 2019;9. doi: 10.1038/s41598-019-56113-7. Cited: in: : PMID: 31862942.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-Non Commercial License that allows others to share the work with an acknowledgment of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
The content of this website is licensed under a Creative Commons Attribution-ShareAlike 4.0 International (CC BY-SA 4.0) license.