Diabetic Ketoacidosis in Type 2 Diabetes Mellitus Patients with a History of Hypertension: Case Report

  • Tri Setyawati Departement of Biochemistry, Faculty of Medicine Tadulako University, Indonesia
  • Sarniwaty Kamissy Departement of Interna, Undata General Hospital-Palu, Indonesia
  • Wisnu Pradhana Merta Medical Profession Program, Faculty of Medicine, Tadulako University, Indonesia
Keywords: Type 2 Diabetes Mellitus, Diabetic Ketoacidosis, Hypertension, Decreased Consciousness

Abstract

Diabetes Mellitus Type 2 is a chronic hyperglycemic disease due to insensitivity of cells to insulin. High glucose levels can cause metabolic problems that occur due to abnormalities in insulin secretion resulting in symptoms of decreased consciousness, a condition known as diabetic ketoacidosis. One of the complications of diabetes is stroke caused by hypertension. This report describes a 69-year-old male patient who was diagnosed with type 2 diabetes mellitus with a history of hypertension who had decreased consciousness. Type 2 Diabetes Mellitus is a hyperglycemic disease due to insensitivity of cells to insulin. Diabetic ketoacidosis (DKA) is an emergency in diabetes mellitus (DM). One of the symptoms that appear such as decreased consciousness, hyperglycemia, Kussmaul breathing. Management should require correction of dehydration, hyperglycemia, acidosis and electrolyte abnormalities, identification of comorbid precipitating factors, and most importantly, continuous patient monitoring.

References

Decroli,E. Diabetes melitus tipe 2. padang :pusat penerbitan bagian ilmu penyakit dalam fakultas kedokteran universitas andalas. 2019.

World Health Organization (WHO). Diabetes. 2008. Diakses pada tanggal 23 juni 2022 tersedia pada http://www.who.int/entity/diabetes

Siregar NN, Soewondo P, Subekti I, Muhadi M. Seventy-two hour mortality prediction model in patients with diabetic ketoacidosis: a retrospective cohort study. J ASEAN Fed Endocr Soc. 2018;33(2):124-9.

Goguen J, Gilbert J. Hyperglycemic emergencies in adults. Can J Diabetes. 2018;42:S109-14.

Gibney MJ., Kearney MJ., Arab L. Gizi Kesehatan Masyarakat. Jakarta: EGC. pp 5. 2009. Guyton AC., Hall JE. Metabolisme Karbohidrat Dan Pembentukan Adenosin Tripospat dalam Buku Ajar Fisiologi Kedokteran. Jakarta: EGC. 2008.

Zhang P, Zhang H, Li X, Chen M, Wang D, Ji L. Factors and outcomes associated with discontinuation of basal insulin therapy in patients with type 2 diabetes mellitus. Endocrinol Diab Metab [Internet]. 2020 Apr [cited 2022 juny 23];3(2). Available from: https://onlinelibrary.wiley.com/doi/abs/10.1002/edm2.122

Nguyen TH, Nguyen T-N, Fischer T, Ha W, Tran TV. Type 2 diabetes among Asian Americans: Prevalence and prevention. WJD. 2015;6(4):543

Gosmanov AR, Gosmanova EO, Kitabchi AE. Hyperglycemic crises: diabetic ketoacidosis (DKA), and hyperglycemic hyperosmolar state (HHS) [Updated 2018 May 17]. In: Feingold KR, Anawalt B, Boyce A,et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279052/

Tjokroprawiro A, Murtiwi S. Kegawatdaruratan diabetes melitus. Dalam: Tjokroprawiro A, Setiawan PB, Effendi C, et al. Buku ajar ilmu penyakit dalam, Edisi 2. Surabaya: Airlangga University Press, 2015. hal.118-25.

Setiyorini E, Wulandari NA, Efyuwinta A. Hubungan kadar gula darah dengan tekanan darah pada lansia penderita Diabetes Tipe 2. JNK JOURNAL. 2018 Aug 27;5(2):163–71.

Mahmudur RS, Quazi TI, Azharul H, Jabed I, Ahmed H, Yousuf UR, et al. Electrolytes Status in Different Type of Acute Stroke Patients and Their Correlation with Some Common Clinical Presentation. Bangladesh Journals Online [Internet] . 2012 [ Cited 2022 juny 23] ;13(2):133-7.

Gariballa SE, Robinson TG, Fotherby MD. Hypokalemia and Potassium Excretion in Stroke Patients. Journals of the American Geriatrics Society [Internet] . 1997 December [ Cited 2022 juny 23];45(12): 1454-8.

Zhulhajsyirah Z, Wahyudin E, Tammas J. EFEKTIVITAS DAN EFEK SAMPING PENGGUNAAN GABAPENTIN PADA PASIEN NEUROPATI DIABETIK DI RSUP DR. WAHIDIN SUDIROHUSODO MAKASSAR. MFF. 2018 Dec 19;22(2):44.

Van Zyl DG. Diagnosis and treatment of diabetic ketoacidosis. SA Fam Prac 2008;50:39-49.

Hyperglycemic crisis in diabetes. Diabetes Care 2004;27(1):94102.

Published
2023-07-13
How to Cite
Tri Setyawati, Sarniwaty Kamissy, & Wisnu Pradhana Merta. (2023). Diabetic Ketoacidosis in Type 2 Diabetes Mellitus Patients with a History of Hypertension: Case Report. International Journal of Health, Economics, and Social Sciences (IJHESS), 5(3), 261-264. https://doi.org/10.56338/ijhess.v5i3.3674
Section
Articles